This script uses the data.frame “data”, loaded from s01.RData. That is, all rows with C==“C” has been excluded for exploratory data analysis.

# ------------------------------------------------------------------
#  Prepare environment
# ------------------------------------------------------------------
# load packages
source(file=file.path("Scripts","Setup","setup01_projectPackages.R")) 
# load output from s01_DatasetPrep.R
load(file=file.path("Scripts","s01.RData"))

# White background in plots
theme_set(theme_bw()) # to be replaced with a azTheme
update_geom_defaults("point", list(shape = 1))

Are the plots and tables also being written to file?

## [1] TRUE

1 Included data

1.1 Plots of occasions included for single dose NCA parameters

Lines connect data from one occasion, points show measured concentrations, the blue horizontal line indicated time of dosing.

1.2 Plots of occasions included for multiple dose/steady state NCA parameters

Lines connect data from one occasion, points show measured concentrations, the blue horizontal line indicated time of dosing.

2 Assessment of PK linearity, \(AUC_{Inf}\) vs dose

2.1 ANOVA

2.2 Linear model

2.3 Power-model

3 Other graphics assessing PK linearity

## quartz_off_screen 
##                 2

3.1 Stratified by single/multiple dose

## quartz_off_screen 
##                 2

4 Assessment of covariate effect on NCA parameters

4.1 Continuous covariates

Add figure text here

## quartz_off_screen 
##                 2

4.2 Categorical covariates

## quartz_off_screen 
##                 2

4.3 Stratified by study

## quartz_off_screen 
##                 2